Nesse episódio do GENE Highlights, gravado durante a 49ª Jornada Paulista de Radiologia, realizada em maio de 2019, em São Paulo, o Dr. Felipe Pacheco entrevista o Dr. Victor Hugo Marussi, que fala sobre as aplicações do imaging genomics em demências. Os episódios do Highlights produzidos durante a 49ª Jornada Paulista de Radiologia, serão publicados às segundas-feiras, no mês de maio até o mês de julho. Serão oito episódios que abordam os assuntos mais relevantes da área da radiologia. A produção conta com o apoio dos grupos de estudos da SPR. A live mencionada pelo Dr. Felipe pode ser consultada no link abaixo: https://www.facebook.com/sociedadepaulistaderadiologia/videos/337162283669582/ Abaixo, seguem os artigos de referência dessa entrevista: Harper L, Barkhof F, Scheltens P, Schott JM, Fox NC. An algorithmic approach to structural imaging in dementia. (2014) Journal of neurology, neurosurgery, and psychiatry. 85 (6): 692-8 - https://www.ncbi.nlm.nih.gov/pubmed/24133287 Murray AD. Imaging approaches for dementia. (2012) AJNR. American journal of neuroradiology. 33 (10): 1836-44 https://www.ncbi.nlm.nih.gov/pubmed/22135130 Olszewska DA, Lonergan R, Fallon EM, Lynch T. Genetics of Frontotemporal Dementia. (2016) Current neurology and neuroscience reports. 16 (12): 107. https://www.ncbi.nlm.nih.gov/pubmed/27878525 Elahi FM, Miller BL. A clinicopathological approach to the diagnosis of dementia. (2017) Nature reviews. Neurology. 13 (8): 457-476. https://www.ncbi.nlm.nih.gov/pubmed/28708131 Conklin J, Silver FL, Mikulis DJ, Mandell DM. Are acute infarcts the cause of leukoaraiosis? Brain mapping for 16 consecutive weeks. (2014) Annals of neurology. 76 (6): 899-904. https://www.ncbi.nlm.nih.gov/pubmed/25283088 Landin-Romero R, Tan R, Hodges JR, Kumfor F. An update on semantic dementia: genetics, imaging, and pathology. (2016) Alzheimer's research & therapy. 8 (1): 52. https://www.ncbi.nlm.nih.gov/pubmed/27915998 Hansen TP, Cain J, Thomas O, Jackson A. Dilated perivascular spaces in the Basal Ganglia are a biomarker of small-vessel disease in a very elderly population with dementia. (2015) AJNR. American journal of neuroradiology. 36 (5): 893-8. https://www.ncbi.nlm.nih.gov/pubmed/25698626 Laveskog A, Wang R, Bronge L, Wahlund LO, Qiu C. Perivascular Spaces in Old Age: Assessment, Distribution, and Correlation with White Matter Hyperintensities. (2018) AJNR. American journal of neuroradiology. 39 (1): 70-76. https://www.ncbi.nlm.nih.gov/pubmed/29170267 Scahill RI, Ridgway GR, Bartlett JW, Barnes J, Ryan NS, Mead S, Beck J, Clarkson MJ, Crutch SJ, Schott JM, Ourselin S, Warren JD, Hardy J, Rossor MN, Fox NC. Genetic influences on atrophy patterns in familial Alzheimer's disease: a comparison of APP and PSEN1 mutations. (2013) Journal of Alzheimer's disease : JAD. 35 (1): 199-212. https://www.ncbi.nlm.nih.gov/pubmed/23380992 Whitwell JL, Weigand SD, Boeve BF, Senjem ML, Gunter JL, DeJesus-Hernandez M, Rutherford NJ, Baker M, Knopman DS, Wszolek ZK, Parisi JE, Dickson DW, Petersen RC, Rademakers R, Jack CR, Josephs KA. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. (2012) Brain : a journal of neurology. 135 (Pt 3): 794-806. https://www.ncbi.nlm.nih.gov/pubmed/22366795 Rohrer JD. Structural brain imaging in frontotemporal dementia. (2012) Biochimica et biophysica acta. 1822 (3): 325-32. https://www.ncbi.nlm.nih.gov/pubmed/21839829 López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. (2013) Cell. 153 (6): 1194-217. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836174/
Comentarios